Primack, J, et al, “LONGITUDINAL ASSESSMENT OF THE SLEEP SUICIDE LINK IN VETERANS: METHODS AND STUDY PROTOCOL”

Jennifer M Primack, McKenzie J Quinn, Mary A Carskadon, Caroline S Holman, Sarra
Nazem, Madeline R Kelsey, Erick J Fedorenko, Sarah McGeary, Leslie Brick, & John
E McGeary

Abstract:

Although sleep disruption has emerged as a theoretically consistent and empirically
supported suicide risk factor, the mechanistic pathways underlying the sleep-suicide link are less understood. This paper describes the methodology of a study intended to examine longitudinal mechanisms driving the link between sleep and suicide in Veterans at elevated suicide risk. Participants will be 140 Veterans hospitalized for suicide attempt or ideation with plan and intent or those identified through the Suicide Prevention Coordinator (SPC) office as being at acute risk. After study enrollment, actigraphy and ecological momentary assessment (EMA) data will be collected for eight weeks, with follow up assessments occurring at two, four, six, eight- and 26-weeks. Participants respond to EMA questionnaires, derived from psychometrically validated assessments targeting emotional reactivity, emotion regulation, impulsivity, suicide risk, and sleep timing constructs, five times a day. First and last daily EMA target sleep parameters including sleep quantity, quality, timing, nightmares, and nocturnal awakenings. During follow-up assessments, participants will complete self report assessments and interviews consistent with EMA constructs and the Iowa Gambling Task. The primary outcome for aim 1 is suicide ideation severity and for the primary outcome for aim 2 is suicide behavior. Findings from this study will improve our understanding of the dynamic interactions among sleep disturbance, emotion reactivity/regulation, and impulsivity to inform conceptual Veteran sleep-suicide mechanistic models. Improved models will be critical to optimizing the precision of suicide prevention efforts that aim to intervene and mitigate risk in Veteran populations, especially during a period of acute risk.

Mendenhall, R, et al, “Lessons (Not) Learned: Chicago Death Inequities during the 1918 Influenza and COVID-19 Pandemics”

Ruby Mendenhall, Jong Cheol Shin, Florence Adibu, Malina Marlyn Yago, Rebecca Vandewalle, Andrew Greenlee and Diana S. Grigsby-Toussaint

Abstract:

During historical and contemporary crises in the U.S., Blacks and other marginalized groups experience an increased risk for adverse health, social, and economic outcomes. These outcomes are driven by structural factors, such as poverty, racial residential segregation, and racial discrimination. These factors affect communities’ exposure to risk and ability to recover from disasters, such as pandemics. This study examines whether areas where descendants of enslaved Africans and other Blacks lived in Chicago were vulnerable to excess death during the 1918 influenza pandemic and whether these disparities persisted in the same areas during the COVID-19 pandemic. To examine disparities, demographic data and influenza and pneumonia deaths were digitized from historic weekly paper maps from the week ending on 5 October 1918 to the week ending on 16 November 1918. Census tracts were labeled predominantly Black or white if the population threshold for the group in a census tract was 40% or higher for only one group. Historic neighborhood boundaries were used to aggregate census tract data. The 1918 spatial distribution of influenza and pneumonia mortality rates and cases in Chicago was then compared to the spatial distribution of COVID-19 mortality rates and cases using publicly available datasets. The results show that during the 1918 pandemic, mortality rates in white, immigrant and Black neighborhoods near industrial areas were highest. Pneumonia mortality rates in both Black and immigrant white neighborhoods near industrial areas were approximately double the rates of neighborhoods with predominantly US-born whites. Pneumonia mortality in Black and immigrant white neighborhoods, far away from industrial areas, was also higher (40% more) than in US-born white neighborhoods. Around 100 years later, COVID-19 mortality was high in areas with high concentrations of Blacks based on zip code analysis, even though the proportion of the Black population with COVID was similar or lower than other racial and immigrant groups. These findings highlight the continued cost of racial disparities in American society in the form of avoidable high rates of Black death during pandemics.

Impact of 5-night sleep restriction on actigraphy-estimated sleep in young adolescents: Preliminary associations with ADHD traits

Gina M. Mason PhD; Taylor G. Christiansen; Victoria O. Dionisos; David H. Barker PhD; Daniel P. Dickstein MD; Mary A. Carskadon PhD; Jared M. Saletin PhD

Mason, G, et al, “Changes in sleep architecture and topography of sleep EEG slow wave activity following acute wake extension in early adolescence”

Gina M. Mason PhD1,2; Victoria O. Dionisos; Taylor G. Christiansen; Daniel P. Dickstein MD; Mary A. Carskadon PhD; Jared M. Saletin PhD

Kemp, J, et al, “Exposure to exposure: A protocol for leveraging exposure principles during training to address therapist-level barriers to exposure implementation”

Joshua Kemp, Kristen Benito, Jennifer Herren, Zoe Brown, Hannah E. Frank and Jennifer Freeman

Abstract:

Background: Exposure therapy is a highly effective but underutilized treatment
for anxiety disorders. A primary contributor to its underutilization is therapist level negative beliefs about its safety and tolerability for patients. Given functional similarities between anxious beliefs among patients and negative beliefs among therapists, the present protocol describes how exposure principles can be leveraged during training to target and reduce therapist negative beliefs.

Methods: The study will take place in two phases. First, is a case-series analysis to
fine-tune training procedures that is already complete, and the second is an ongoing
randomized trial that tests the novel exposure to exposure (E2E) training condition
against a passive didactic approach. A precision implementation framework will
be applied to evaluate the mechanism(s) by which training influences aspects of
therapist delivery following training.

Anticipated results: It is hypothesized that the E2E training condition will produce
greater reductions in therapists’ negative beliefs about exposure during training
relative to the didactic condition, and that greater reduction in negative beliefs
will be associated with higher quality exposure delivery as measured by coding of
videotaped delivery with actual patients.

Conclusion: Implementation challenges encountered to date are discussed
along with recommendations for future training interventions. Considerations for
expansion of the E2E training approach are also discussed within the context of
parallel treatment and training processes that may be tested in future training trials

Frank, H, et al, “Therapist perceptions of experiential training for exposure therapy”

Hannah E. Frank, Lara S. Rifkin, Kate Sheehan, Emily M. Becker-Haimes,
Margaret E. Crane, Katherine E. Phillips, Sophie A. Palitz Buinewicz, Joshua Kemp,
Kristen Benito and Philip C. Kendall

Abstract:

Background: Despite evidence for its efficacy, exposure therapy for anxiety is rarely used in routine care settings. Efforts to address one major barrier to its use – therapists’ negative beliefs about exposure – have included therapist-level implementation strategies, such as training and consultation. Experiential training, in which therapists themselves undergo exposures, has recently demonstrated feasibility, acceptability and preliminary effectiveness for increasing exposure use.

Aims: This study aimed to assess: (1) therapists’ perceptions of experiential training and (2) barriers and facilitators to implementing exposure following training.

Method: Therapists who underwent experiential training (n = 12) completed qualitative interviews and quantitative questionnaires. Interviews were coded using an integrated approach, combining both inductive and deductive approaches. Mixed methods analyses examined how themes varied by practice setting (community mental health versus private practice) and exposure use.

Results: Results highlight how therapist-level factors, such as clinician self-efficacy, interact with inner and outer-setting factors. Participants reported positive perceptions of exposure after training; they noted that directly addressing myths about exposure and experiencing exposures themselves improved their attitudes toward exposure. Consistent with prior literature, issues such as insufficient supervisory support, organizational constraints, and client characteristics made it challenging to implement exposures.

Discussion: Results highlight the benefits of experiential training, while also highlighting the need to consider contextual determinants. Differences in responses across practice settings highlight areas for intervention and the importance of tailoring implementation strategies. Barriers that were specific to therapists who did not use exposure (e.g. hesitancy about its appropriateness for most clients) point to directions for future implementation efforts.

Parent-identified barriers to accessing exposure therapy: A qualitative study using process mapping

Frank HE, Cain G, Freeman J, Benito KG, O’Connor E, Kemp J, Kim B. Front Psychiatry. 2023 Mar 20;14:1068255. doi: 10.3389/fpsyt.2023.1068255. PMID: 37020732; PMCID: PMC10067909.

Frank, H, et al, “Expanding the reach of evidence-based mental health interventions to private practice: Qualitative assessment using a policy ecology framework”

Hannah E. Frank, Lauren Milgram, Jennifer B. Freeman,
and Kristen G. Benito

Abstract:

Background: Evidence-based interventions (EBIs) for mental health disorders
are underutilized in routine clinical practice. Exposure therapy for anxiety
disorders is one particularly difficult-to-implement EBI that has robust
empirical support. Previous research has examined EBI implementation
determinants in publicly funded mental health settings, but few studies have
examined EBI implementation determinants in private practice settings. Private
practice clinicians likely face unique barriers to implementation, including
setting-specific contextual barriers to EBI use. The policy ecology framework
considers broad systemic determinants, including organizational, regulatory,
social, and political contexts, which are likely relevant to EBI implementation
in private practice settings but have not been examined in prior research.

Methods: Qualitative interviews were conducted to assess private practice
clinicians’ perceptions of EBI implementation determinants using the policy
ecology framework. Clinicians were asked about implementing mental health
EBIs broadly and exposure therapy specifically. Mixed methods analyses
compared responses from clinicians working in solo vs. group private
practice and clinicians who reported high vs. low organizational support for
exposure therapy.

Results: Responses highlight several barriers and facilitators to EBI
implementation in private practice. Examples include determinants related to
organizational support (e.g., colleagues using EBIs), payer restrictions (e.g.,
lack of reimbursement for longer sessions), fiscal incentives (e.g., payment
for attending training), and consumer demand for EBIs. There were notable differences in barriers faced by clinicians who work in group private practices compared to those working in solo practices. Solo private practice clinicians described ways in which their practice setting limits their degree of colleague support (e.g. for consultation or exposure therapy planning), while also allowing for flexibility (e.g. in their schedules and practice location) that may not be available to clinicians in group practice.

Conclusions: Using the policy ecology framework provides a broad
understanding of contextual factors that impact private practice clinicians’ use
of EBIs, including exposure therapy. Findings point to potential implementation
strategies that may address barriers that are unique to clinicians working in
private practice.

Daniels, T, et al, “Associations of Restraint and Seclusion With Race and Ethnicity on an Adolescent Inpatient Psychiatric Service”

Teresa E Daniels, Colleen Victor, Eric M Smith, Christa Belgrave, Erica Robinson,
Jennifer C Wolff, Jeffrey Hunt, Elizabeth H Brannan

Abstract:

There is limited work examining the association of race and ethnicity with restraint and seclusion (R/S) in pediatric inpatient psychiatric units. The present study assessed risk of R/S by race and ethnicity based on a retrospective review of electronic medical records (EMRs) from an adolescent inpatient psychiatric service. Demographic, diagnostic, and R/S data were analyzed for all 1,865 admissions of 1,327 patients from an adolescent unit at a child and adolescent psychiatric hospital from June 2018 to June 2021. R/S occurred in 459 of the admissions. For the purpose of patient privacy and statistical analysis, race was grouped into the following: Black or African American, other (American Indian or Alaskan Native, Asian, multiracial, other), and White. Patients identified as unknown were not included in the analysis. A binary logistic regression with a repeated subject effect regressed R/S onto race and adjusted for age, gender, and length of stay (LOS). There was an overall significant association of R/S and race (χ = 16.81, p < .001), but not ethnicity. In a regression model adjusted for age, gender, and LOS, patients identified as Black or African American were at significantly higher risk of R/S compared with patients identified as White (odds ratio = 1.66, p = .036). There was no significant difference in risk of R/S between patients identified as White vs other. Younger age and longer LOS were also significantly associated with R/S. These findings highlight a critical health care disparity related to race on an inpatient adolescent psychiatry service. There is likely a combination of individual and systemic factors leading to discriminatory practices in the use of R/S. Future work will assess potential associations with diagnosis and child welfare involvement and will examine additional characteristics of R/S. Focus groups held with hospital and community stakeholders will guide next steps to address these findings.

ADHD traits and psychomotor vigilance after 5 nights of experimental sleep and restriction in early adolescence: preliminary results

Taylor G. Christiansen, BA, Victoria O. Dionisos, BS; Gina M. Mason, PhD; David H. Barker, PhD; Daniel P. Dickstein, MD; Mary A. Carskadon, PhD; Jared M. Saletin, PhD