Honoring Our Longest-Serving Employees: Mary Carskadon, PhD, a Pioneer of Sleep Science

PROVIDENCE, R.I. [Brown University Health Intranet] — Preparing to speak with Mary Carskadon, PhD, one of the world’s most respected sleep researchers – well, it might just keep you up at night.
Brown Alumni Magazine declared her a “pioneering sleep scientist” who is “still discovering new frontiers.” A recipient of the National Sleep Foundation’s Lifetime Achievement Award, Carskadon is the director of the sleep and chronobiology research lab and the director of the COBRE Center for Sleep and Circadian Rhythms in Child and Adolescent Mental Health, both with Bradley Hospital. She is also a professor with the department of psychiatry and human behavior at The Warren Alpert Medical School of Brown University.

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Biological clock plays critical role in driving teens’ late-day eating habits

Researchers found that adolescents in the obese weight range ate more food later in the day than their peers of healthy weight, and that their eating behaviors were strongly influenced by their internal body clock.

PROVIDENCE, R.I. [Brown University] — The causes of obesity are complex and influenced by many factors. While research has highlighted connections between sleep, eating patterns and weight gain, scientists remain uncertain of the role of the circadian system — the biological clock — in shaping eating patterns.

But a new study from researchers at the Warren Alpert Medical School of Brown University and Mass General Brigham reveals a distinct relationship between circadian rhythms, weight and eating habits in adolescents, a vulnerable age group whose eating patterns influence their lifelong health. The study found that adolescents whose weight was classified as overweight or obese consumed more calories later in the day compared to participants with healthy weights.

The results demonstrate that circadian rhythms play an important role in explaining later caloric intake in individuals at risk for obesity, said lead investigator Mary Carskadon, a professor of psychiatry and human behavior at Brown’s medical school.

“The critical nature of adolescent development to set the stage for a lifetime of health highlights the need to understand the roles played by sleep/wake and circadian timing processes for eating behavior,” said Carskadon, who also directs the Bradley Hospital Sleep Research Laboratory. “The knowledge gained here opens a door to potential interventions that can enhance teen health moving forward.”

The results were published in the Proceedings of the National Academy of Sciences.

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Time to Death by Suicide in an Epidemiological Sample of Veterans With an Inpatient Hospitalization for Heart Failure

Bozzay ML, Thompson MF, Jiang L, Primack JM, McGeary JE, De Vito AN, Browne J, Kelso CM, Rudolph JL, Kunicki ZJ. Time to Death by Suicide in an Epidemiological Sample of Veterans With an Inpatient Hospitalization for Heart Failure. Am J Geriatr Psychiatry. 2025 Feb 18:S1064-7481(25)00038-7. doi: 10.1016/j.jagp.2025.02.005. Epub ahead of print. PMID: 40021417.

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Molecular insights into trauma: A framework of epigenetic pathways to resilience through intervention

Merrill SM, Konwar C, Fraihat Z, Parent J, Dajani R. Molecular insights into trauma: A framework of epigenetic pathways to resilience through intervention. Med. 2025 Feb 14;6(2):100560. doi: 10.1016/j.medj.2024.11.013. Epub 2024 Dec 20. PMID: 39708797.

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Multi-site feasibility and fidelity of remote yoga intervention to improve management of type-2 diabetes: Design and methods of the HA1C (Healthy Active and In Control) study

Thind H, Pekmezi D, Dunsiger S, Guthrie KM, Stroud L, Wu WC, Walaska K, Bock BC. Multi-site feasibility and fidelity of remote yoga intervention to improve management of type-2 diabetes: Design and methods of the HA1C (Healthy Active and In Control) study. Contemp Clin Trials. 2025 Apr;151:107842. doi: 10.1016/j.cct.2025.107842. Epub 2025 Feb 10. PMID: 39938612; PMCID: PMC11911072.

Multi-site feasibility and fidelity of remote yoga intervention to improve management of Type 2 diabetes

What works for whom in pediatric OCD: description of causally interpretable meta-analysis methods and report on trial data harmonization

Norris LA, Barker DH, Rosen AR, Kemp J, Freeman J, Benito KG; Project Harmony Team. What works for whom in pediatric OCD: description of causally interpretable meta-analysis methods and report on trial data harmonization. Psychol Med. 2025 Feb 6;55:e27. doi: 10.1017/S0033291724003301. PMID: 39911021; PMCID: PMC12017367.

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So Long, SLEEP Advances…

Carskadon MA. So Long, SLEEP Advances…. Sleep Adv. 2025 Feb 4;6(1):zpaf006. doi: 10.1093/sleepadvances/zpaf006. PMID: 39906876; PMCID: PMC11792890.

 

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Behavioral and sociodemographic correlates of sleep duration among children in Samoa

von Ash T, Choy CC, Dunsiger S, Soti-Ulberg C, Wang D, Reupena MS, Duckham RL, Naseri T, Hawley NL. Behavioral and sociodemographic correlates of sleep duration among children in Samoa. Sleep Health. 2025 Feb;11(1):57-64. doi: 10.1016/j.sleh.2024.10.009. Epub 2025 Jan 1. PMID: 39753399; PMCID: PMC11805616.

Behavioral and sociodemographic correlates of sleep duration among children in Samoa

Childhood adversity and adolescent epigenetic age acceleration: the role of adolescent sleep health

DiMarzio K, Rojo-Wissar DM, Hernandez Valencia E, Ver Pault M, Denherder S, Lopez A, Lerch J, Metrailer G, Merrill S, Highlander A, Parent J. Childhood adversity and adolescent epigenetic age acceleration: the role of adolescent sleep health. Sleep Adv. 2025 Jan 31;6(1):zpaf003. doi: 10.1093/sleepadvances/zpaf003. PMID: 39896753; PMCID: PMC11783326.

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COBRE Center Pilot Grad wins Presidential Early Career Award

We are proud to announce that pilot project graduate, Justin Parent, PhD, has been awarded the Presidential Early Career Award!  This distinguished honor recognizes his contributions to science and his work in epigenetics. While this award celebrates his outstanding early career achievements, we invite you to explore a recent manuscript in Sleep Advances that illustrates his work: https://pmc.ncbi.nlm.nih.gov/articles/PMC11398434/. Please join us in congratulating Dr. Parent on this honor! We look forward to seeing the continued impact of his work.